Please use this identifier to cite or link to this item: http://ciateq.repositorioinstitucional.mx/jspui/handle/1020/177
Toxicology of antimicrobial nanoparticles for prosthetic devices
Rosa Elvira Nuñez-Anita
Laura Susana Acosta_Torres
JUAN CARLOS MARTINEZ ESPINOSA
Javier De La Fuente Hernández
VICTOR MANUEL CASTAÑO MENESES
Acceso Abierto
Atribución-NoComercial-CompartirIgual
1178-2013
https://www.dovepress.com/toxicology-of-antimicrobial-nanoparticlesfor-prosthetic-devices-peer-reviewed-article-IJN
10.2147/IJN.S63064
Cytotoxicity
Oxidative stress
Genotoxicity
Antifungal effect
Denture bases
Advances in nanotechnology are producing an accelerated proliferation of new nanomaterial composites that are likely to become an important source of engineered health-related products. Nanoparticles with antifungal effects are of great interest in the formulation of microbicidal materials. Fungi are found as innocuous commensals and colonize various habitats in and on humans, especially the skin and mucosa. As growth on surfaces is a natural part of the Candida spp. lifestyle, one can expect that Candida organisms colonize prosthetic devices, such as dentures. Macromolecular systems, due to their properties, allow efficient use of these materials in various fields, including the creation of reinforced nanoparticle polymers with antimicrobial activity. This review briefly summarizes the results of studies conducted during the past decade and especially in the last few years focused on the toxicity of different antimicrobial polymers and factors influencing their activities, as well as the main applications of antimicrobial polymers in dentistry. The present study addresses aspects that are often overlooked in nanotoxicology studies, such as careful time-dependent characterization of agglomeration and ion release.
The authors thank the following DGPA-UNAM supporting programs: PAPIME-PE202214 and PAPIIT-TA200414. Victor M Castaño is on sabbatical leave at CIATEQ-Queretaro.
Dovepress
2014
Artículo
International Journal of Nanomedicine, vol. 9, no. 1, p. 3999-4006
Inglés
Público en general
OTRAS ESPECIALIDADES MÉDICAS
Versión publicada
publishedVersion - Versión publicada
Appears in Collections:Artículos Publicados en Revistas Indexadas

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