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http://ciateq.repositorioinstitucional.mx/jspui/handle/1020/79| Mapping knowledge translation and innovation processes in cancer drug development: the case of liposomal doxorubicin | |
| David Fajardo-Ortiz VICTOR MANUEL CASTAÑO MENESES | |
| Acceso Abierto | |
| Atribución | |
| 1479-5876 | |
| https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-014-0227-9 https://doi.org/10.1186/s12967-014-0227-9 | |
| 10.1186/s12967-014-0227-9 | |
| Drug development Innovation change Liposomes Neoplasm Translational medicine | |
| We explored how the knowledge translation and innovation processes are structured when theyresult in innovations, as in the case of liposomal doxorubicin research. In order to map the processes, a literature network analysis was made through Cytoscape and semantic analysis was performed by GOPubmed which is based in the controlled vocabularies MeSH (Medical Subject Headings) and GO (Gene Ontology). We found clusters related to different stages of the technological development (invention, innovation and imitation) and the knowledge translation process (preclinical, translational and clinical research), and we were able to map the historic emergence of Doxil as a paradigmatic nanodrug. This research could be a powerful methodological tool for decision-making and innovation management in drug delivery research. | |
| Biomed Central Ltd | |
| 03-09-2014 | |
| Artículo | |
| Journal of Translational Medicine 2014, 12:227 | |
| Inglés | |
| Público en general | |
| OTRAS ESPECIALIDADES MÉDICAS | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos Publicados en Revistas Indexadas |
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| Fichero | Tamaño | Formato | |
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| Mapping knowledge translation and innovation.pdf | 3.8 MB | Adobe PDF | Visualizar/Abrir |